Post-extrasystolic potentiation differentiates “true” from “pseudo” Low-flow, Low-gradient aortic stenosis

Main Article Content

Marc Vanderheyden*
Sofie Verstreken
Marc Goethals

Abstract

Post-extrasystolic potentiation (PESP) is a marker of contractile reserve and refers to the augmentation of left ventricular contractility due to preload recruitment and rise in intracellular calcium following a premature beat. In this case report we show that PESP might be a safe and helpful aid to evaluate low flow, low gradient aortic stenosis and contractile reserve in the cathlab, thereby reducing the potential risk of complications associated with intravenous dobutamine evaluation and reducing unnecessary testing.

Article Details

Vanderheyden, M., Verstreken, S., & Goethals, M. (2020). Post-extrasystolic potentiation differentiates “true” from “pseudo” Low-flow, Low-gradient aortic stenosis. Journal of Cardiology and Cardiovascular Medicine, 5(3), 172–173. https://doi.org/10.29328/journal.jccm.1001105
Research Articles

Copyright (c) 2020 Vanderheyden M, et al.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

The Journal of Cardiology and Cardiovascular Medicine is committed in making it easier for people to share and build upon the work of others while maintaining consistency with the rules of copyright. In order to use the Open Access paradigm to the maximum extent in true terms as free of charge online access along with usage right, we grant usage rights through the use of specific Creative Commons license.

License: Copyright © 2017 - 2025 | Creative Commons License Open Access by Journal of Cardiology and Cardiovascular Medicine is licensed under a Creative Commons Attribution 4.0 International License. Based on a work at Heighten Science Publications Inc.

With this license, the authors are allowed that after publishing with the journal, they can share their research by posting a free draft copy of their article to any repository or website.

Compliance 'CC BY' license helps in:

Permission to read and download
Permission to display in a repository
Permission to translate
Commercial uses of manuscript

'CC' stands for Creative Commons license. 'BY' symbolizes that users have provided attribution to the creator that the published manuscripts can be used or shared. This license allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author.

Please take in notification that Creative Commons user licenses are non-revocable. We recommend authors to check if their funding body requires a specific license. 

Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017; 38: 2739–2791. PubMed: https://pubmed.ncbi.nlm.nih.gov/28886619/

Wisenbaugh T, Nissen S, DeMaria A. Mechanics of postextrasystolic potentiation in normal subjects and patients with valvular heart disease. Circulation. 1986; 74: 10–20. PubMed: https://pubmed.ncbi.nlm.nih.gov/2423268/

Domingo E, Angel J, Alvarez A, Anivarro I, Soler‐Soler J. Postextrasystolic potentiation of systolic gradient in valvular aortic stenosis: Clinical usefulness and analysis of hemodynamic factors. Catheter Cardio Diag. 1987; 13: 381–390. PubMed: https://pubmed.ncbi.nlm.nih.gov/2446771/

Wiley BM, Pollack A, Vaidya AS, Agarwal SK, Sengupta PP, et al. Post-Extrasystolic Transaortic Valve Gradients Differentiate “Pseudo” and “True” Low-Flow, Low-Gradient Severe AS During Dobutamine Stress Echocardiography. Jacc Cardiovasc Imaging. 2017; 10: 1199–1200. PubMed: https://pubmed.ncbi.nlm.nih.gov/28109925/

Bhave NM, Patel AR, Shah AP, Lang RM. Postextrasystolic Potentiation in Low‐Gradient, Severe Aortic Stenosis: A Poor Man’s Stress Echo? Echocardiogr. 2013; 30: E148–151. PubMed: https://pubmed.ncbi.nlm.nih.gov/23551839/